Aspartic Acid Proteases as Therapeutic Targets, Volume 45 by Arun K. Ghosh

By Arun K. Ghosh

during this ground-breaking sensible reference, the kin of aspartic acid proteases is defined from a drug developer's viewpoint. the 1st half presents a normal advent to the relations of aspartic acid proteases, their physiological capabilities, molecular constitution and inhibition. elements to 5 current quite a few case reviews of winning protease inhibitor drug layout and improvement, in addition to present and power makes use of of such inhibitors in pharmaceutical medication, protecting the main healing ambitions HIV-1 protease, renin, beta-secretase, gamma-secretase,plasmepsins and fungal proteases.
A prepared reference aimed essentially at execs within the pharmaceutical undefined, in addition to for someone learning proteases and their function.

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