Pharmamarketing: Ein Leitfaden für die tägliche Praxis by Thomas Trilling

By Thomas Trilling

Das erste praxisbezogene Buch für (angehende) Produktmanager in der Pharma- und Medizinprodukteindustrie: Praxisnah und für den täglichen Einsatz konzipiert, beschreibt der Autor alle wichtigen Aspekte des Pharmamarketing, weist auf mögliche Fallstricke hin und gibt praktische Hilfestellungen für die Planung und Durchführung von Marketing-Projekten. Sein Praxisleitfaden ist ein zuverlässiger Assistent für Produktmanager. Die 2., aktualisierte und verbesserte Auflage enthält besonders wertvolle Checklisten für jede Marketingmaßnahme mit allen wichtigen Arbeitsschritten. Ein Muss für alle, die selbstverantwortlich Marketing-Projekte durchführen.

Show description

Continue Reading

Drugs for HER-2-positive Breast Cancer (Milestones in Drug by Maria Sibilia,Christoph C. Zielinski,Rupert Bartsch,Thomas

By Maria Sibilia,Christoph C. Zielinski,Rupert Bartsch,Thomas W. Grunt

Growth issue receptors have lengthy been identified to force malignant transformation and melanoma development. The epidermal progress issue receptor (EGFR, ErbB, HER) process is probably going the easiest defined membrane receptor tyrosine kinase relatives in malignant tumors. With implementation of the growth-inhibitory anti-HER-2 antibody trastuzumab (Herceptin) for the remedy of HER-2-positive complicated metastatic breast melanoma, a brand new period has dawned within the treatment of this malignant illness. regrettably, trastuzumab-sensitive cancers normally boost resistance to the antibody after a while. fresh medical reports have printed that those refractory tumors are nonetheless conscious of inhibition of the HER receptor kinfolk utilizing twin HER-1/-2 inhibitors reminiscent of lapatinib (Tykerb/Tyverb). furthermore, a multiplicity of novel, superior irreversibly appearing small molecular HER tyrosine kinase inhibitors are within the pipeline of many drug constructing businesses and are being evaluated within the medical setting.

Show description

Continue Reading

TRP Channels as Therapeutic Targets: From Basic Science to by Arpad Szallasi

By Arpad Szallasi

TRP Channels as healing pursuits: From simple technological know-how to scientific Use is authored by way of specialists throughout academia and undefined, supplying readers with an entire photograph of the healing power and demanding situations linked to utilizing TRP channels as drug ambitions.

This booklet bargains a special medical process by means of protecting compounds that focus on TRP channels in pre-clinical and medical stages, additionally delivering a dialogue of TRP channels as biomarkers.

An complete part is dedicated to the unconventional and cutting edge makes use of of those channels throughout a number of ailments, supplying recommendations that may be used to beat the hostile results of first new release TRPV1 antagonists.

Intended for all researchers and clinicians operating towards the improvement of winning medicines concentrating on TRP channels, this booklet is a vital source chocked packed with the most recent medical facts and findings.

  • Contains finished insurance of TRP channels as healing ambitions, from rising scientific symptoms to accomplished scientific trials
  • Discusses TRP channels as tested goals, starting from weight problems and diabetes via melanoma and respiration problems, kidney illnesses, high blood pressure, neurodegenerative problems, and more
  • Provides serious research of the problems and unwanted side effects that experience surfaced in the course of scientific trials, supplying evidence-based feedback for overcoming them

Show description

Continue Reading

Cannabinoids: 168 (Handbook of Experimental Pharmacology) by Roger G. Pertwee (Ed.),Roger G. Pertwee

By Roger G. Pertwee (Ed.),Roger G. Pertwee

below twenty years in the past the ?eld of hashish and the cannabinoids used to be nonetheless c- sidered a minor, a little bit old fashioned, quarter of analysis. a couple of teams have been lively within the ?eld, however it was once already being considered as stagnating. The chemistry of hashish nine nine was once renowned, ? -tetrahydrocannabinol (? -THC), identi?ed in 1964, being the single significant psychoactive constituent and cannabidiol, which isn't psychoactive, probably contributing to a few of the consequences. those cannabinoids and a number of other s- thetic analogs have been completely investigated for his or her pharmacological results. Their mode of motion was once thought of to be non-speci?c. the explanations for this - sumption have been either technical and conceptual. at the technical part, it have been proven that THC used to be lively in either enantiomeric kinds (though with a distinct point of efficiency) and this remark was once incompatible with motion on organic substrates—a receptor, an enzyme, an ion channel—which react with a unmarried stereoisomer purely. The conceptual challenge on the topic of THC task. This were mentioned by way of numerous very popular learn teams that had proven that the various results obvious with cannabinoids have been regarding these of biologically lively lipophiles, and that the various results of THC, rather continual ones, have been corresponding to these noticeable with anaesthetics and solvents.

Show description

Continue Reading

The SAGE Encyclopedia of Pharmacology and Society by Sarah E. Boslaugh

By Sarah E. Boslaugh

The SAGE Encyclopedia of Pharmacology and Society explores the social and coverage aspects of the pharmaceutical and its pervasive impact in society. whereas many technical STM works discover the chemistry and biology of pharmacology and an both huge variety of clinically orientated works concentrate on use of unlawful medicines, substance abuse, and therapy, there's almost not anything at the immensely large company (“Big Pharma”) of constructing, promoting, eating, and regulating criminal medications.


With this new Encyclopedia, the subject of socioeconomic, enterprise and shopper, and criminal and moral problems with the pharmaceutical in modern society around the globe are addressed.


Key Features:

  • 800 signed articles, authored by means of sought after students, are prepared A-to-Z and released in a decision of digital or print formats
  • Although prepared A-to-Z, a Reader's advisor within the entrance subject groups articles through thematic areas
  • Front topic additionally incorporates a Chronology highlighting major advancements during this field
  • All articles finish with Further Readings and pass References to comparable articles
  • Back topic contains an annotated source consultant to additional study, a word list, Appendices (e.g., data at the quantity and kinds of gear prescribed, etc.), and a detailed Index
  • The Index, Reader’s advisor, and move References mix for search-and-browse services within the digital edition 


The SAGE Encyclopedia of Pharmacology and Society is an authoritative and rigorous resource addressing the pharmacology and the way it impacts society, making it vital reference for all educational libraries as a resource for either scholars and researchers to utilize.



Show description

Continue Reading

Neuroimaging Pharmacopoeia by Daniel Thomas Ginat,Juan E. Small,Pamela Whitney Schaefer

By Daniel Thomas Ginat,Juan E. Small,Pamela Whitney Schaefer

This ebook experiences the imaging positive factors linked to chosen sessions of prescription drugs and medication on mind, head and neck, and backbone and explains the consequences of the imaging findings for the neuroradiologist and the clinician. a few brokers produce attribute abnormalities with precise imaging positive aspects, whereas others have a spectrum of manifestations on imaging. nonetheless extra brokers produce quite nonspecific adjustments on imaging, requiring a differential analysis. during this e-book, informative instances are depicted through wealthy photographs, with concise accompanying explanatory textual content that studies the category of agent and the mechanism of motion and discusses snapshot interpretation and its importance.

Show description

Continue Reading

McGraw-Hill's 2016/2017 Top 300 Pharmacy Drug Cards by Jill M. Kolesar,Lee Vermeulen

By Jill M. Kolesar,Lee Vermeulen

The top and simplest way to profit crucial information regarding the head three hundred drugs

Includes lately authorized hepatitis C vaccines

Every card includes:

  • Generic and customary name
  • Class
  • Dosage Forms
  • Approved Dose and Indications
  • Off-Label Use
  • Contraindications
  • Adverse Reactions
  • Drug Interactions
  • Monitoring Parameters
  • Medication questions of safety and Black field Warnings
  • Clinical pearls that support advisor sufferer care
  • Strong concentrate on sufferer safety

This variation is superior by way of eleven new playing cards, key grownup and pediatric immunization vaccines, and MP3 audio obtain with distinct dialogue of every drug.

Show description

Continue Reading

ADMET for Medicinal Chemists: A Practical Guide by Katya Tsaioun,Steven A. Kates

By Katya Tsaioun,Steven A. Kates

This e-book courses medicinal chemists in the way to enforce early ADMET checking out of their workflow that allows you to enhance either the rate and potency in their efforts. even though many pharmaceutical businesses have devoted teams at once interfacing with drug discovery, the medical ideas and techniques are practiced in numerous other ways. This publication solutions the necessity to regularize the drug discovery interface; it defines and experiences the sphere of ADME for medicinal chemists. additionally, the medical rules and the instruments used by ADME scientists in a discovery surroundings, as utilized to medicinal chemistry and constitution amendment to enhance drug-like homes of drug applicants, are examined.

Show description

Continue Reading

Alcohol and Cancer by Samir Zakhari,Vasilis Vasiliou,Q. Max Guo

By Samir Zakhari,Vasilis Vasiliou,Q. Max Guo

the area healthiness association has pointed out continual alcohol intake as one of many most sensible ten possibility components for around the world burden of ailment. The overseas business enterprise for study on melanoma has pointed out alcohol as carcinogenic to people, together with cancers of the higher aerodigestive tract, colon, liver and breast. Alcohol’s activities will be direct e.g. results on retinoic acid and one-carbon metabolism, or oblique, via metabolites reminiscent of acetaldehyde and reactive oxygen species or via a variety of signaling pathways that effect phone cycle and apoptosis which may give a contribution to carcinogenesis. This document experiences the cutting-edge in alcohol-related melanoma study in ten chapters.

Show description

Continue Reading

Development of Therapeutic Agents Handbook (Pharmaceutical by Shayne Cox Gad

By Shayne Cox Gad

A complete examine present drug discovery and improvement methods—and the roadmap for the future

Providing either knowing and counsel in characterizing power medicines and their creation and synthesis, Development of healing brokers Handbook provides execs a easy device to facilitate examine and improvement inside of this difficult procedure. This finished textual content brings jointly, in a single source, a compendium of ideas, ways, methodologies, and obstacles that have to be thought of within the formula of healing brokers throughout a number healing fields. either a reference and a decision to motion for the pharmaceutical undefined, Development of healing brokers Handbook examines contemporary concepts taking form within the a number of scientific disciplines focused on drug discovery, and indicates why those advances must be embraced universally between researchers to enhance their answer ideas. extra subject material includes:

  • Extensive insurance and in-depth check out novel remedies and therapeutics

  • Discussion of scorching subject matters like new medicinal drugs and nutraceuticals, the invention and improvement of vaccines, melanoma therapeutics, and industry overviews

  • Coverage of healing drug improvement for particular disorder parts, similar to cardiology, oncology, breast melanoma, and kidney diseases

As examine in biology, chemistry, drugs, and expertise swiftly progresses, it's changing into more and more vital for clinical researchers to take care of an updated wisdom base of rising tendencies directing promising new remedies. Development of healing brokers Handbook serves this function, performing as either a one-stop reference wealthy in legitimate technological know-how, and a device to carve out new pathways within the pursuit of bringing more secure and better medicines to the marketplace.

Show description

Continue Reading